The flip side of Dapoxetine use: is it safe?

The Flip Side of Dapoxetine Use: Is It Safe?

The Flip Side of Dapoxetine Use: Is It Safe?

Dapoxetine is a popular substance for the treatment of premature ejaculation, which is successfully used around the world. Is it safe or harmful to health? How to make the drug effective and harmless? You will learn about this in the article below.

This substance was created as an antidepressant, but because of rapid excretion from the body, it is not suitable for the treatment of depression.

All selective serotonin reuptake inhibitors (one of the classes of antidepressants) have an unusual side effect – they reduce libido, inhibit sexual function, and are able to delay orgasm. Dapoxetine does not last long in comparison with antidepressants, so its side effect can be used to treat premature ejaculation (PE). This is the only selective serotonin reuptake inhibitor that is used for such purposes. Priligy is a quite popular and effective drug, but its price is as high as the quality, so this medication is not available to all men. For men who want to save their money, there are quality and inexpensive generics based on dapoxetine which act exactly like Priligy.

Dapoxetine Vs Premature Ejaculation

Drugs based on dapoxetine are very popular. At the moment they do not have FDA approval, but their quality is confirmed by a lot of research and by men who were able to get rid of PE. At the moment they are used in more than fifty countries around the world. So, in 2018 they are freely sold in pharmacies in Spain, Uruguay, Sweden, Italy, Germany, France, South Korea, the Philippines, New Zealand, Portugal, Austria, Australia, Argentina, Mexico, and Malaysia.

The flip side of Dapoxetine use: is it safe

Studies which were conducted on men 18 to 82 years of age say that dapoxetine is well-tolerated and suitable for most men from 18 to 65 years old, and for older people its intake is recommended. The most popular dosages are 30mg and 60mg.

Dapoxetine is most effective in the treatment of PE caused by psychological reasons. According to statistics, in the vast majority of cases, the too rapid onset of orgasm is caused precisely by psychological factors. The drug is not addictive, and it can be used for a long time.

Research results have shown that 30 mg of dapoxetine can increase the sexual act from 0.9 minutes to 3.1 minutes, and 60 mg up to 3.6 minutes. Men who were given “dummies” instead of the drug noted that the sex act, which lasted less than a minute began to last twice as long. This confirms the fact that PE is usually caused by psychological causes, so it is easily treatable with dapoxetine. 31% of men in the placebo group confirmed that now they can better control ejaculation with the help of a “medication.”

Who Must Avoid Dapoxetine Intake?

Dapoxetine is well-tolerated and safe, provided that a person does not have contraindications.

AllergiesThe main list of them includes the following:

  • hypersensitivity to the drug components;
  • severe heart and vascular disease;
  • heavy renal and hepatic insufficiency;
  • serious mental disorders (mania, bipolar disorder, schizophrenia, paranoia, etc.);
  • depression;
  • tendency to fainting;
  • epilepsy;
  • mood swings;
  • glaucoma and high ocular pressure;
  • allergic reaction to the drug.

If none of the listed afflicts you, then dapoxetine will be absolutely safe.

Side Effects of Dapoxetine

Any potent substance can cause side effects, and dapoxetine is not an exception. The risk of side effects from generic drugs based on dapoxetine always exists, but it is significantly less when taking 30 mg of dapoxetine than when taking 60 mg. It is possible to get rid of unwanted symptoms by halving the dosage. If this does not work, then the drug should be stopped. All side effects should disappear after excretion of dapoxetine from the body. If this does not happen or if side effects increase, it is necessary to consult with a doctor. Side effects, in most cases, appear after the first or second tablet, so at this time do not drive a car, and if possible, try to stay at home.


With the strict observance of prescribing information and the absence of contraindications, generics based on dapoxetine are well-tolerated and rarely cause side effects, but they still can occur. With dependence of dosage there can be such undesirable symptoms:

Side effect Likelihood, %
30 mg 60 mg
Nausea 11 22,2
Dizziness 5,8 10,9
Headache 5,6 8,8
Diarrhea 3,5 6,9
Drowsiness 3,1 4,7

InsomniaSlightly less often there can be:

  • insomnia;
  • fatigue;
  • nasal congestion;
  • depression;
  • anorgasmia, decreased libido;
  • blurred vision;
  • rush of blood;
  • violation of the heart rate (tachycardia, bradycardia);
  • ringing in the ears;
  • yawning;
  • hyperhidrosis;
  • bloating;
  • dry mouth;
  • increased blood pressure;
  • asthenia.


The rare side effects include:

  • sudden falling asleep;
  • dizziness during physical exercises;
  • hot flushes.

As you can see, the listed side effects are not dangerous for health and life if you care about your safety. For example, fainting can lead to falls and injuries if you are on the street during the action of dapoxetine.

The drug is not addictive, but in rare cases, after its stoppage, there may be insomnia, anxiety, and dizziness.

Adverse Effects of Dapoxetine + Sildenafil

Often PE is combined with erectile dysfunction (ED), and in this case dapoxetine can play a nasty trick on a man. This drug prolongs sexual intercourse but somewhat inhibits the libido, which makes a person with ED unable to have sex. In such situations, dapoxetine is advisable to use together with PDE5 (phosphodiesterase 5) inhibitors, for example, sildenafil or tadalafil. They suppress PDE5 enzymes, which stop the erection, and also improve blood circulation, contributing to the complete filling of the penis with blood. An erection with sildenafil is natural since this drug acts only with sexual arousal.

Sildenafil lasts up to four or five hours and works well with dapoxetine. These drugs do not react chemically with each other, and therefore it is safe to take them together if there are no contraindications. It is important to know that the use of dapoxetine with sildenafil can have additional side effects.

Side effects of medicinesThese include:

  • lowering of blood pressure;
  • impaired color perception, especially blue and green;
  • muscle pain;
  • redness of the skin;
  • urticaria.

Side effects can be noticeable as long as the active substances stay in your system (about eight hours).

The most popular drug based on sildenafil is Viagra, produced by Pfizer. There are also many quality and less expensive generics – Kamagra, Viagra Soft, generic Viagra, etc., and medicines containing both sildenafil and dapoxetine, for example, Super P-Force 160 mg. They can be bought OTC at SildenafilViagra online pharmacy.

About Side Effects of Dapoxetine & Tadalafil

Tadalafil is also often used together with drugs for PE. It is well-tolerated, and its interaction with dapoxetine is not a threat to health. The effectiveness of this drug is high enough, and it is suitable for most men, including those who are older than 65 years of age. The prolonged action makes it really unique. How long does the effect last? Producers say that tadalafil acts up to 36 hours – this is equal to its half-life.

Tadalafil has the same side effects as sildenafil, but they are less common since this medication has a softer effect. The most popular drug on its basis is Cialis. Also, there are more affordable, but no less effective drugs, including generic Cialis, Tadarise, Tadagra, Cialis Soft, etc. As is the case with sildenafil, there are drugs with a combination of dapoxetine and tadalafil. One of the most famous among them is Tadapox.

Dapoxetine Interaction

Alcohol drinksDapoxetine is a fairly convenient drug that can be combined with most medications. It does not require changes in habits or lifestyle, and it has good tolerability. You can do the work, sports, and other activities while taking it. However, there are some limitations, and they must be taken into account.

If you are constantly using any medications, consult with your doctor first, because there is a possibility that these drugs cannot be taken with dapoxetine. If after the intake of dapoxetine you feel really bad, it is also advisable to consult with a specialist.

Mixing with Alcohol Drinks

Producers do not recommend taking alcohol together with drugs based on dapoxetine. This can lead to a strong sedative effect, drowsiness, dizziness, and fainting. If this happens when a person is not at home, then such effects can lead him to injury. However, doctors say that a small amount of alcohol can be tolerated. The fact is that alcohol with premature ejaculation can help the situation because it relieves stress and slightly reduces sensitivity. What can be considered as a small amount of alcohol? This can be a glass of wine or one bottle of beer. If this dosage is exceeded, the likelihood of side effects will be increased. If you decide to take alcohol with the medicine for the first time, try to stay at home.

Dapoxetine and Food

This medicine can be taken during meals or before/after them. This is due to the fact that dapoxetine does not interact chemically with food. The only thing that can affect food is the rate of absorption of the medicine. Fatty foods can delay the start of the medicine’s effect for a while, but it does not reduce it.

The only product that cannot be eaten with dapoxetine is grapefruit. It is able to significantly reduce the effectiveness of the drug and slow its elimination period from the body. Because of this, the risk of side effects increases. This applies not only to grapefruit, but also to its derivatives – juice, fresh, jelly, etc.

Combination with Other Pills

AntidepressantsThe safety of dapoxetine is guaranteed by its proper combination with other medicines. The prohibited combination options include:

  • St. John’s wort;
  • lithium;
  • tramadol;
  • tryptophan;
  • tricyclic antidepressants;
  • drugs used for HIV treatment;
  • thioridazine;
  • other selective serotonin reuptake inhibitors;
  • MAO inhibitors;
  • active inhibitors of CYP3A4.

The drug contains lactose, so people with intolerance to this component should also abstain from taking dapoxetine.

If you have any chronic disease, it is advisable to consult with a doctor before buying dapoxetine. It is also important to do this if you are constantly taking any over-the-counter medication.

Some sedative drugs, including those of herbal origin, can do harm if taken together with dapoxetine, so be careful.

In Which Cases It Can Be Harmful?

Dapoxetine will be absolutely safe if you follow the instructions exactly, do not exceed the dosage, and do not allow its interaction with some of the medicines listed above. However, there are also several recommendations that will make taking this medication even more effective and safe.

If you are taking dapoxetine for the first time, then do not drive a car, as dizziness, confusion, and short-term vision impairment are possible. Also, it is not recommended taking alcohol if you are not convinced that dapoxetine is good for you and does not cause any side effects.

WaterBe prepared for the fact that after taking pills, dizziness may occur when you change your body position quickly. To avoid this, try to move smoothly and avoid sudden movements. Also, take the tablet with plenty of water, then lie down for a while.

In rare cases, dapoxetine can cause suicidal thoughts. If this happens to you, then the drug should be immediately stopped. The same goes for mood swings if they started while using the medication.

Usage of only quality tested generics is very important, because they are sold without a prescription. To do this, you need to find out which manufacturers supply the medicine, find the best-proven pharmacy, read a review of it, and testimonials of those who have had experience of shopping there.

Generics of Dapoxetine: Where to Buy Cheap Medicine?

A lot of people who have decided to get rid of PE ask themselves a question – where can I buy a cheap and high-quality medicine? If you want to buy a dapoxetine-based drug at a bargain price, then the SildenafilViagra online pharmacy is just what you are looking for. We have a lot of drugs for the treatment of PE, such as Kutub, Sustinex, and other generic alternatives. Also, here you will find medicines with several uses, intended for the treatment of both PE and erectile dysfunction.

In addition, at the SildenafilViagra store there are various generic drugs for the treatment of impotence which are presented for sale. None of them are inferior to the original drugs in quality, but they are manufactured in India and thanks to this do not have markup for a brand name, making their cost quite cheap.

Online orderOur website offers not only favorable prices, but also many ways to save money. By making a wholesale order, you will significantly reduce the cost of each tablet and paying with bitcoins gives a 35% discount.

All our regular customers get a bonus of $25 and an additional 30 free tablets with each new purchase. If all of this is not enough, there is also free delivery with tracking tool that is available (when buying a certain amount).

SildenafilViagra offers the possibility to test the quality of production for free, by making an order for a trial pack of medicines. Your order will be delivered to any USA city in the shortest possible time.